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00049_Field_SRC.p12.C.17.txt
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1997-01-28
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4. Infuse the marrow stem cells intravenously.
In a typical bone marrow transplant unit, the day on which the marrow is given is referred to as Day 0. The
other days you spend in the hospital are numbered as either a plus or minus, counting from the day the
marrow is infused.
5. Manage the complications until the marrow produces enough normal blood
cells and, in an allogeneic transplant , until graft-versus-host disease
is controlled.
While the high-dose therapy is often uncomfortable, the period after the marrow infusion is the most
dangerous. This is when the bone marrow cells begin to proliferate, ideally to the point where the marrow
will produce enough red cells, white cells and platelets. This is when you run the risk of infections and
bleeding problems. Most patients who don't survive long after a bone marrow transplant die from infections
or the effects of graft-versus-host disease after the new marrow starts to grow.
Until you recover adequate white blood cell and platelet counts, you will be kept under close medical
observation, usually in a special hospital room. After the marrow starts to grow, you will stay under close
medical supervision until it is clear that the new marrow is functioning properly, that there has been no
serious graft-versus-host disease and that your cancer has been controlled.